eCM Meeting Abstracts 2016, Collection 4
eCM XVII - Stem Cells, Bone Fixation, Repair & Regeneration
June 20-23, 2016, Convention Centre, Davos Platz, Switzerland
Abstracts of the meeting
The hosting of this years conference abstracts was kindly sponsored by
All abstracts: click here to download all the abstracts in one file
Oral presentations, followed by Posters
Page 1: C Hartmann
Wnt signaling in bone development and regeneration
Page 2: WEG Müller, XH Wang
Evolution of the mineralized animal skeletons: Formation of bone hydroxyapatite via amorphous Ca-carbonate and Ca-phosphate
Page 3: M Pacifici
The biology of heterotopic endochondral ossification and approaches to therapy
Page 4: E Farrell
Endochondral ossification in regenerative medicine
Page 5: K Sivasubramaniyan, WJ Koevoet, EJ Farrell, M Sande, JAN Verhaar, GJVM. Osch
Mesenchymal stem cell heterogeneity: Diversity in the endogenous synovial stem cell compartment
Page 6: G Orsini, P Pagella, L Jimenez-Rojo, M Procaccini, A Putignano, TA Mitsiadis
Fate of dental epithelial stem cells in vivo injected in the mouse incisor
Page 7: J Li, YH Liang, WJ Peng, TH Chen, ML Zhou, GQ Zhou
Gene expression profiling shows the desregulation of multiple hormone signaling in osteoporosis that could be therapeutically reversed by the treatment of strontium gluconate
Page 8: B Péault
Mesenchymal stem cells: where is the stem..?
Page 9: B Johnstone
Chondral cell differentiation
Page 10: AE Rapp, R Bindl, M Rojweski, J Kemmler, H Schrezenmeier, I Müller, A Ignatius
Autogenic mesenchymal stromal cells (MSC) are superior to allogenic MSC in regeneration of large bone defects
Page 11: A Tekari, R May, DA Frauchiger, HJ Sebald, LM Benneker, B Gantenbein
The osteogenic differentiation of mesenchymal stromal cells is enhanced by the BMP2 variant L51P in the presence of intervertebral disc-derived cells
Page 12: AJ El Haj
Growth environments and cues for engineering bone tissue in vitro
Page 13: DW Hutmacher
Additive Biomanufacturing – The rationale to change the current paradigm by changing the question from “what can we do with this method?” to “how can we change this technology platform to achieve what we need for Skeletal Tissue Engineering & Regenerative Medicine”.
Page 14: KC Hung, CS Tseng, LG Dai, SH Hsu
Water-based polyurethane 3D printed scaffolds with controlled release function for customized osteochondral tissue engineering
Page 15: O Guillaume, M Geven, U Eberli, S Zeiter, D Grijpma, M Alini, D Eglin
Introduction of a new biodegradable composite implant for bone repair: poly(trimethylene carbonate)-hydroxyapatite made by stereolithography
Page 16: DW Weisgerber, C Flanagan, X Ren, SJ Hollister, JC Lee, MB Wheeler, BAC Harley
Multi-scale mineralized collagen-polycaprolactone composites for craniofacial bone tissue engineering
Page 17: D Logeart-Avramoglou
Engineered bone for the repair of large bone defects: The challenge of implanted MSC survival
Page 18: V Glatt
The influence of mechanical environment in bone healing
Page 19: F Saxer, A Scherberich, A Todorov, P Studer, S Miot, S Schreiner, S Güven, LAH Tchang, M Haug, M Heberer, DJ Schaefer, D Rikli, M Jakob, I Martin
Direct use of freshly-isolated adipose-derived cells for fracture augmentation in a first-in-man phase I clinical trial
Page 20: U Ripamonti, R Duarte, RM Klar, R Parak, C Dickens, T Dix-Peek
The new regenerative frontiers in cranio-mandibulo-facial surgery in primates: The pleiotropic inductive activities of the mammalian TGF-β3 isoform
Page 21: PM Tufekci, A Tavakoli, C Dlaska, M Neumann, M Shanker, S Saifzadeh, M Schuetz, DR Epari
Can confining stimulation to the proliferative phase promote a sufficient healing outcome?
Page 22: M Herrmann, S Zeiter, U Eberli, M Hildebrand, K Camenisch, U Menzel, M Alini, S Verrier, V Stadelmann
Improved fracture healing by short-term G-CSF treatment
Page 23: MJ Allen
Choosing the right animal model for bone-related questions
Page 24: R Müller
Reducing the use of animals by in vivo imaging of bone and blood vessels
Page 25: S Fahmy-Garcia, D Mumcuoglu, L de Miguel, BCJ van der Eerden, D Eglin, SGJM Kluijtman, GJVM van Osch, E Farrell
Injectable synthetic collagen beads hydrogel loaded with BMP2 promotes ectopic bone formation
Page 26: B Li, U Menzel, C Loebel, M Alini, MJ Stoddart
Identification and isolation of live mesenchymal stem cells based on differentiation induced changes in mRNA expression
Page 27: SR Caliari, JL Holloway, SL Vega, JA Burdick
Hydrogels to control and recruit stem cells
Page 28: M Bohner
Synthetic bone fillers: how important is the micro and macrostructure?
Page 29: J Bolander, W Ji, J Leijten, V Bloemen, L Moreira Teixeira, D Lambrechts, FP Luyten
Healing of a critical size long bone defect through a serum free biomimetic cell-based approach
Page 30:*** A Barba, K Rappe, P Fontecha, A Diez-Escudero, Y Maazouz, M Espanol, C Öhman, C Persson, MC Manzanares, J Franch, MP Ginebra
Biomimetic nanostructured calcium phosphate scaffolds: osteoinduction and osteogenesis
***Robert Mathys Foundation winner of the award for the best oral presentation by a student
Page 31: S Lauber Fürst
Why young companies will shape the MedTech World
Page 32: G Szekely
Public support on the steep and thorny way from spinoff to market success
Page 33: X Li, E Bachmann
A novel product and market entry challenges for a young medtech startup
Page 34: JD de Bruijn
A materials approach to bone regeneration: From idea to market
Page 35: G Perale
Biohybrid materials: inspired by nature to repair bones
Page 36: K Schmidt-Bleek, C Schlundt, C Bucher, A Serra, T ElKhassawna, S Wendler, H Wagner, HD Volk, GN Duda
The adaptive immune system impacts bone healing processes
Page 37: S Fuchs
The role of angiogenesis in bone repair
Page 38: GQ Zhou, XL Li, T Liu, TH Chen, J Li, Y Zhu, YH Liang, ML Zhou
Small molecule Kartogenin promotes cartilage regeneration through activating IL-6-based mesenchymal stem cell proloferation
Page 39: L Leitão, CJ Alves, IS Alencastre, DM Sousa, E Neto, C Leitão, G Almeida-Porada, M Lamghari
In vivo bone marrow and cytokine dynamics in two experimentally injured tissues
Page 40: A Lunger, MG Burger, A Grosso, P Briguez, JA Hubbell, D Schaefer, A Banfi, N Di Maggio
Effective vascularization and efficient bone formation in osteogenic grafts requires VEGF dose control
Page 41: J Buschmann, E Balli, SC Hess, WJ Stark, P Cinelli, S Märsmann, M Welti, W Weder, W Jungraitmayr
Adipose-derived stem cell seeded biominerizable nanocomposite for chest wall repair: suppression of inflammatory response in a murine model
Page 43: GI Im
Clinical use of stem cells
Page 44: C Götherström, C DeVile, R Sakkers, O Semler, E Åström
BOOSTB4: a clinical study on pre- and/or postnatal stem cell transplantation for treatment of osteogenesis imperfecta
Poster presentations
Page 45: HW Chien, HY Chen, J Yu, WB Tsai
In situ poly(carboxybetaine) hydrogel for bone tissue application
Page 46: E Choinska, W Swieszkowski
Novel approach to control drug release and adherence of PLA based implant coatings
Page 47:*** L Freitag, C Günther, L Kyllönen, U Eberli, K Thompson, D Arens, S Zeiter, D Eglin, VA Stadelmann
The efficacy of local bisphosphonate and BMP-2 delivery in improving bone mass and mechanical implant stability
***Robert Mathys Foundation winner of the award for the best poster presentation by a student
Page 48: D Harvanova, T Spakova, J Plsikova, J Amrichova, S Hornak, J Rosocha
Critical size bird bone defect healed with xenogeneic ostrich cancellous bone grafts seeded with aviary bone cells – experimental bird model
Page 49: L Huo, LW Zheng
Effect of zoledronate on periodontitis in a compromised rat model
Page 50: L Juignet, B Charbonnier, V Dumas, C Laurent, L Vico, D Marchat, N Douard, L Malaval
Impact of cell substrate curvature on matrix deposition and osteoblastic behavior
Page 51: V Kauschke, M Schneider, A Jauch, M Kampschulte, M Schumacher, M Gelinsky, C Heiss, KS Lips
A new metaphyseal implant associated fracture healing model applied in osteoporotic knockout mice
Page 52: MKE Koolen, A Longoni, AJWP Rosenberg, HH Weinans, D Gawlitta
Chondrogenically differentiated xenogeneic MSCs in endochondral bone regeneration
Page 53: J Li, YH Liang, ZY Zhou, WM Zhu, WJ Peng, GQ Zhou
Human intra-articular stem cells isolated during arthroscopy surgery as a new cell source with high potential for cartilage regeneration
Page 54: C Neidlinger-Wilke, GQ Teixeira, A Rapp, D Kletsas, A Ignatius
Chondrogenic differentiation of bone marrow derived stem cells (MSCs) versus adipose derived stem cells (ASCs) at pro-inflammatory conditions
Page 55: J Plsikova, D Harvanova, T Spakova, S Gromosova, M Lacko, T Kluka, J Sevc, J Rosocha
The effects of human bone grafts on osteogenic differentiation of adipose tissue derived mesenchymal stromal cells in vitro
Page 56: NP Quirk, A Thoreson, RE De la Vega, MJ Coenen, M Trujillo, CM Lopez De Padilla, S Tepic, CH Evans
Characterization of a novel dynamizable external fixator for ovine tibial segmental defects
Page 57: AJ Rahyussalim, DY Pranatha, T Kurniawati
One year follow up on hybrid system in spinal tuberculosis surgery
Page 58: AJ Rahyussalim, I Saleh, T Kurniawati, MT Wijaya, AY Safri
Single concave correction technique for main thoracic curve scoliosis Lenke Classification type 1
Page 59: AJ Rahyussalim, T Kurniawati, D Aprilya, R Anggraini, Y Whulanza, G Ramahdita
Toxicity and biocompatibility profile of scaffold developed by Universitas Indonesia on mesenchymal stem cells: A preliminary study
Page 60: AJ Rahyussalim, I Saleh, T Kurniawati, MT Wijaya, AY Safri
Implant failure after posterior instrumentation on extreme and progressive congenital scoliosis with some comorbidities: 4 years follow up
Page 61: T Spakova, J Plsikova, D Harvanova, M Lacko, J Rosocha
Effect of in vitro differentiation of human mesenchymal stem cells on cartilage repair in osteoarthritis of knee joint
Page 62: CM Sprecher, SF Schindele, S Hensler, S Milz
Osteointegration in a CapFlex-PIP© finger implant: a histological case report
Page 63: M Tohidnezhad, T Heigl, N Barahmand Pour, C Bergmann, M Bienert, P Lichte, HC Pape, S Neuss Stein, H Fischer, T Pufe
Regeneration of critical size bone defects via the implantation of novel ß tricalcium phosphate scaffolds in transgenic mice
Page 64: A Woloszyk, TA Mitsiadis
Human dental pulp stem cells stabilize blood vessels by secreting vascular basement membrane proteins collagen type IV and laminin in ovo
Page 65: F Yang, SCF Rawlinson, KA Hing
Osteoblast-like cells seeded on 3D bone graft scaffold with hierarchical pore structure are responsive to mechanical loading
Page 66: KC Yang, HH Hu, IH Chen, CC Wang
Influence of scaffold geometry on chondrocyte fate to tissue engineered cartilage
Page 67: BG Yun, SH Park, SH Hwang, MH Lim,SA Back, JH Jeon, SW Kim
Promotion of the osteogenic differentiation potential of human nasal inferior turbinate-derived mesenchymal stem cells by mechanical memory
Page 68: JJ Bara, I Dresing, S Zeiter, M Anton, G Daculsi, D Eglin, D Nehrbass, VA Stadelmann, DC Betts, R Müller, M Alini, MJ Stoddart
A tuneable, adenoviral BMP-2 gene delivery system to bone
Page 69: C Moser, K Bardsley C Wolfrum, AJ El Haj, M Alini, MJ Stoddart, JJ Bara
Perfusion culture regulates the differentiation of mesenchymal stromal cells on polylactic-glycolic acid in vitro
All abstracts: click here to download all the abstracts in one file