eCM Meeting Abstracts 2023, Collection 1
2023 eCM21: Bone and Fracture Repair
Meeting Abstracts
Oral presentations: click here to download all the abstracts in one file
Poster presentations: click here to download all the abstracts in one file
Oral presentations
Page 1: H Simpson
The non-union timeline: when is the fate of a fracture decided?
Page 2: P Giannoudis, H Owston, E Jones
Stem cells for bone repair: a clinical perspective
Page 3: D Hoey
Targeting mechanosignalling to modulate bone repair
Page 4: A Pitsillides
Bone mechanoadaptation – local to whole-organ considerations
Page 5: M Windolf, L Hofmann-Fliri, R Gurung, D Epari
From basic research to patient benefit – the journey of the biphasic plate
Page 6: M Keiser, S Preiss, SJ Ferguson, VA Stadelmann
Subchondral bone migrates into trabecular bone in response to direct bone-on-bone contact wear in patients with severe knee osteoarthritis
Page 7: P Füllemann, T Jörimann, M Stoddart, R Matthys, S Verrier
Mechanical strain triggers naïve MSCs in vitro differentiation towards hypertrophic chondrocytes
Page 8: V Glatt
Biomimetic hematoma to enhance bone healing: current status and future clinical implications
Page 9: LWH Cheung
External biomechanical stimulation as an approach to stimulate fracture healing
Page 10: E Gomez-Barrena
Clinical trials on expanded MSCs for bone regeneration
Page 11: S James Habib
A novel bandage for bone repair
Page 12: A Banfi
The interplay of angiogenesis and osteogenesis for bone regeneration
Page 13: M Schröder, L Gens, L Bernhard, D Ahrens, D Gehweiler, S Zeitler, M Stoddart, E Wehrle
Effects of low dose BMP-2 on cytokine levels during fracture healing in a femur segmental defect in rats
Page 14: R Randriantsilefisoa, G Miklosic, EI Bektas, M D'Este
Filling the gaps: dynamic alginate-hydroxyapatite composite for bone tissue regeneration
Page 15: SW Verbruggen, J Nolan, MP Duffy, OMT Pearce, CR Jacobs, MM Knight
A TGF-β cross-talk mechanism, in both breast and prostate cancer, which disrupts osteocyte primary cilia-mediated regulation of bone metastases
Page 16: M Haffner-Luntzer, B Weber, K Morioka, I Lackner, V Fischer, CS Bahney, A Ignatius, M Kalbitz, R Marcucio, T Miclau
Multi-organ crosstalk during bone fracture healing - interplay between brain trauma, bone and the immune system
Page 17: C Capobianco, M Song, E Farrell, A Donneys, A Knights, K Kessell, T Maerz, K Hankenson
Utilizing single cell RNA sequencing to study poor fracture healing
Page 18: Esther Wehrle
Individualized omics-based preclinical models for bone healing
Page 19: MR Iaquinta, R De Pace, A D’Agostino, L Trevisiol, F Lonardi, M Bersani, M Tognon, F Martini, E Mazzoni
Release of stem cell paracrine factors, and bone regrowth in patients, induced by composite scaffold
Page 20: M Stewart, J Nguyen- Edquilang
Transient TGF-β exposure activates BMP-dependent periosteal osteogenesis
Page 21: J Barcik, M Schröder, D Arens, L Gens, D Mischler, D Gehweiler, S Zeiter, P Varga, M Stoddart, E Wehrle
Longitudinal monitoring of healing progression via in vivo stiffness measurements in a mouse femur defect model
Page 22: M van Griensven, R Groven, ER Balmayor, M Poeze, TJ Blokhuis
miRNAs play a pivotal role in fracture healing
Page 23: ER Balmayor
cmRNA and its delivery for bone regeneration
Page 24: Y-C Hu
Intelligent CRISPR design for bone regeneration
Page 25: EB McGlinch, JA Panos, MJ Coenen, MA Barry, CH Evans
Vector engineering and development for osseous nonunions
RMS Best Student Oral Presentation
Page 26: M Wiesli, S Kiderlen, A González-Vásquez, K Maniura, M Rottmar, W Lackington
Improving mineralization in a novel fracture hematoma model via delivery of IL-10 and BMP-7
Page 27: RE de la Vega, MJ Coenen, GP Hawse, JA Panos, A Atasoy-Zeybek, CV Nagelli, CH Evans
Feasibility of use of a non-osteogenic, genetically modified cell line for large bone regeneration in a rat femoral segmental defect model
Page 28: D Cadoux-Hudson, J Kanczler, K Dexter, S Tilley, N Evans
Demonstrating microbubble perfusion and cavitation within a murine critical calvarial defect
Page 29: L Nicolescu, A Antoniac,I Antoniac
Biodegradable magnesium alloys for trauma implants
Page 30: FE Weber
3D-printed bone substitutes for osteoconduction and bone augmentation: When architecture meets biology
Page 31: J Vecstaudza, CM Sprecher, M D’Este, J Locs, E Della Bella
Osteoclastic resorption of calcium phosphate-based materials is influenced by the crystallization pathway
Page 32: D Van der Heide, LP Hatt, E Della Bella, H Yuan, F De Groot-Barrère, MJ Stoddart, M D'Este
3D printed composite resembling natural bone by combining hyaluronan, collagen and calcium phosphate to promote bone regeneration
RMS Best Student Oral Presentation
Page 33: L Sicard, S Maillard, DM Akoa, C Chaussain, T Coradin
Chitosan-modified dense collagen hydrogels loaded with anti-sclerostin antibodies as biomaterials for critical size calvaria defect repair
Page 34: M Laubach, B Herath, N Bock, S Suresh, S Saifzadeh, BL Dargaville, S Cometta, V Schemenz, J McGovern, ML Wille, FM Savi, DW Hutmacher
In vivo study of 3D-printed polycaprolactone-hydroxyapatite scaffolds with Voronoi design to advance the concept of scaffold-guided bone regeneration
Page 35: V Fischer, D Ragipoglu, M Haffner-Luntzer, J Kroner, A Dudeck, A Ignatius
Mast cells - Crucial modulators in osteoporotic fracture healing
Page 36: R Osinga, M Morgenstern, M Clauss, D Schaefer
Role of soft tissue in fracture-related infection (FRI) and periprosthetic joint infection (PJI)
Page 37: A Pylostomou, R Tognato, JK Wychowaniec, M D'Este, JR Weiser, T Serra, D Loca, A Vernengo
Thermosensitive support baths promoting aligned anisotropic stem cell clustering for endochondral bone tissue engineering
Page 38: MEA Tschaffon-Müller, E Kempter, MR Kuhn, F Gebhard, M Kalbitz, K Schütze, H Gündel, N Kaleck, K Weimer, A Ignatius, SO Reber, M Haffner-Luntzer
Chronic psychosocial stress disturbs fracture healing via catecholamies produced by immune cells
Page 39: T Fabian Mertens, A Tabea Liebheit, A Fiedler, R Köhler, W Liublin, R Günther, A Rakhymzhan, R Niesner, AE Hauser
Analyzing bone regeneration in time and space: novel approaches for multi-modal, multi-dimensional imaging
Page 40: C Arrigoni, S Bersini, G Talò, D Petta, M Moretti
Engineering 3D human multicellular bone in vitro models as anti-tumor drug screening systems
Page 41: I Toillon, S Ferrari, M Gerbaix
Alterations of bone microarchitecture and bone fragility in a type 1 diabetes mouse model (akita mice)
Page 42: M Milošević, I Banićević, N Jaćimović, M Miola, F Baino, E Verné, J Stojkovska, B Obradović
Biomimetic alginate-based scaffolds with bioactive glass particles as a relevant in vitro model of bone tissue
Page 43: I Banicevic, M Milosevic, J Petrović, K Menshikh, M Milivojevic, M Stevanovic, R Jankovic, A Cochis, J Stojkovska, L Rimondini, B Obradovic
A 3D cell culture model mimicking pathological and physiological conditions in bone
Page 44: LP Hatt, AR Armiento, MJ Stoddart
β-TCP from 3D-printed scaffold can act as an effective phosphate source during the osteogenic differentiation of human mesenchymal stromal cell
RMS Best Student Oral Presentation
Page 45: BD Crist
Berton Rahn Research Award winner 2023 (booklet)
RIA versus BMC as orthobiologic augments to allografts
Poster presentations
Page P1: J Barcik, M Ernst, T Buchholz, C Constant, S Zeiter, S Verrier
Short-term response of bone related markers over stimulatory and resting periods – case series conducted on sheep
Page P2: D Cadoux-Hudson, M Thomas, J Hurst, R Schranz, A Gerrish, K Wallace, D Warwick, D Carugo, E Stride, S Tilley, ND Evans
Contrast-enhanced ultrasound imaging of displaced humeral fractures: Results of a pragmatic single-centre study
Page P3: E Chatzopoulou, N Bousaidi, T Guilbert, G Rucher, J Rose, S Germain, François Rouzet, C Chaussain, L Muller, C Gorin
Dental Pulp Stem cells facilitate the engineering of 3D functional revascularized constructs
Page P4: Effect of therapeutic IL1Ra and IL10 mRNA vehiculated by polymeric nanoparticles in osteochondral ex-vivo model: a new approach for osteoarthritis treatment V Basoli, A Traweger, C Plank, J Rip, M Alini, S Grad
Page P5: W Lackington, B Bellon, P Schweizer, A Ambeza, AL Chopard-Lallier, A Armutlulu, P Schmutz, X Maeder, M Rottmar
Enhanced osseointegration using biomimetic laser-textured implants
Page P6: V Oberlohr, M MacKechnie, P Robles, MJ Flores, M Rio, S Iriarte, V Giordano, JE Quintero, D Escalante, JA Xicará, L Padilla, D Aguilar, J Segovia, I Escalante, T Miclau, on behalf of the ACTUAR Hip Fracture Study Group
Femoral neck fracture care in Latin America
Page P7: MA Mohn, A Kadow-Romacker, S Yanc, K Schmidt-Bleek, W Gerdes, GN Duda
Activated CD31+ cells from peripheral blood positively impact osteogenesis
Page P8:L Nicolescu, A Antoniac, I Antoniac
Influence of testing environment on the degradation behaviour of magnesium alloys for orthopaedic implants
Page P9: RA Saß, CH Bucher, IK Na, O Penack, GN Duda, K Schmidt-Bleek
Hematopoietic stem cell transplantation alters bone structure and influences bone homeostasis